Whiteboard Chemistry with Joe White

Introduction to organic chemistry

The six ways to represent a molecule (including skeletal formulae), IUPAC naming, homologous series and functional groups, structural and E–Z isomerism, and the curly-arrow language of mechanisms.

AQA 7404/7405 Paper 2
CCCCOHHHHHHHHHH OH
Building on GCSE

From C7 Organic Chemistry you already know alkanes and alkenes, functional groups and homologous series, and that carbon forms four bonds. A-Level adds the full representation toolkit — especially skeletal formulae — systematic IUPAC naming, the three types of structural isomerism plus E–Z stereoisomerism, and the curly-arrow language that every organic reaction on Paper 2 is written in. This page is the toolkit; the reactions build on it.

The six formulae

A molecule can be written six ways, and A-Level expects you to move between them — and to give the exact one asked for. Each strips away or adds detail:

RepresentationWhat it showsExample (butan-1-ol)
Empiricalsimplest whole-number ratio of atomsC4H10O — already simplest (cf. ethane C2H6 → CH3)
Molecularthe actual number of each atomC4H10O
Generalthe algebraic pattern for the seriesCnH2n+1OH
Structuralthe arrangement, condensedCH3CH2CH2CH2OH
Displayedevery atom and every bond shownall C, H and O drawn with lines
SkeletalC and C–H implied; only the skeleton & groupsa zig-zag ending in –OH

One molecule — butan-1-ol, C4H10O — three ways AQA can ask for it

Structural

CH3CH2CH2CH2OH

condensed to one line — no bonds drawn

Displayed

CCCCOHHHHHHHHHH

every atom and every bond — including O–H

Skeletal

OH

C at every corner & line-end; C–H implied; OH still drawn

Not skeletal

CCCCOH

the carbons are never written in

Not displayed

CCCCOHHHHHHHHHH

“OH” hides a bond — displayed must draw the O–H

Bond to the O — never the H

OH HO

the atom facing the chain must be the O (chain–OH, or HO–chain when the group points left). In the lower drawing the bond lands on the H — that reads C–H–O, a bond to the wrong atom

Skeletal keeps carbons and their hydrogens implied — a carbon at every corner and line-end — but the –OH is always drawn. Displayed shows everything, including each O–H.
Skeletal formula — the conventions

Carbon atoms are not written: there is a carbon at every corner and at the end of every line. Hydrogens bonded to carbon are left out. But every heteroatom (O, N, halogen…) is drawn, and any hydrogen bonded to it (so –OH, –NH2, –COOH are shown in full).

Precision points
  • Skeletal is not displayed — the format is worth marks. Examiner reports flag a displayed formula given when a skeletal one was asked for (and vice versa). Read the command word and answer in exactly that form.
  • Always draw the –OH. In both skeletal and displayed, the oxygen and its hydrogen are shown; hiding the O–H in a displayed formula loses the mark.
  • The bond reaches the O, never the H. The connectivity is C–O–H, so the oxygen faces the chain: chain–OH, or HO–chain when the group points left. A bond drawn to the H reads C–H–O — a different (impossible) molecule.
  • Terminal groups are line-ends, not bare corners. A chain ending in CH3 is the end of a line; count the implied hydrogens so the carbon has four bonds.

Homologous series & functional groups

Organic chemistry is organised into families. Each family — a homologous series — is built around one functional group, the reactive part that decides how the molecule behaves.

Key definition

A homologous series is a family of compounds with the same functional group and the same general formula, in which each member differs from the next by CH2. Members have similar chemical properties and a gradual trend in physical properties.

One piece of shorthand before the chart: R stands for “the rest of the molecule” — any alkyl group (CH3–, CH3CH2–…). So R–OH means any alcohol and R–Br any bromoalkane; where two chains can differ they are written R and R′ (an ester is R–COO–R′). X is used the same way for “any halogen”.

SeriesFunctional groupGeneral formulaNamed with
AlkaneC–C single bondsCnH2n+2-ane
AlkeneC=CCnH2n-ene
HalogenoalkaneC–X (X = halogen)CnH2n+1Xchloro-/bromo-/iodo-
Alcohol–OHCnH2n+1OH-ol
Aldehyde–CHO (end of chain)CnH2nO-al
KetoneC=O (within chain)CnH2nO-one
Carboxylic acid–COOHCnH2n+1COOH-oic acid
Ester–COO–CnH2nO2-oate
Amine–NH2CnH2n+3Namino- / -amine
Nitrile–C≡NCnH2n+1CN-nitrile
The functional group is the reactive handle: it names the family and drives its chemistry, whatever the chain length. Example drawn for each — note where the group sits.
Precision points
  • General formula is the pattern; functional group is the family. The general formula (CnH2n+2…) generates every member; the functional group decides the reactions.
  • Aldehydes and ketones share CnH2nO but are different series — the C=O is at the end (aldehyde) or within the chain (ketone).
🧪 Exam-style questions
Q1 [1 mark]

Which is the correct general formula for the non-cyclic compounds in the homologous series? Tick (✓) one box.

Q2 [1 mark]

Which compound has the lowest relative molecular mass? Tick (✓) one box.

Source: AQA A-Level Chemistry past papers.

Naming: the IUPAC rules

Every organic name is built from the same four parts, in this order of decisions:

  1. Stem — find the longest carbon chain that contains the main functional group: meth (1), eth (2), prop (3), but (4), pent (5), hex (6). A ring adds cyclo-.
  2. Suffix — the principal functional group (the highest-priority group present — see below) sets the ending: -ane, -ene, -ol, -al, -one, -oic acid…
  3. Locants — number the chain from the end that gives the functional group (then the substituents) the lowest numbers.
  4. Prefixes — add substituents (methyl-, chloro-…) with their locants, in alphabetical order, using di/tri for repeats.

What if a molecule carries two functional groups? The higher-priority group wins the suffix (and the lowest locant); everything it outranks is named around it. The priority order for the groups on this page:

carboxylic acid  >  aldehyde  >  ketone  >  alcohol  >  amine  >  alkene

So CH2=CHCH2OH is prop-2-en-1-ol: the OH outranks the C=C, so it takes the -ol suffix and carbon 1, while the double bond stays in the name as -en-. Halogens and alkyl branches are always prefixes (2-bromo…, 3-methyl…) — they never take the suffix — and an outranked OH appears as the prefix “hydroxy-”.

OH1234 3-methylbutan-2-ol substituentstemlocantsuffix
Build a name in that order — longest chain, principal group, lowest locants, alphabetical prefixes — and reverse it to draw a structure from a name. Number so the locants are as low as possible: here the OH takes 2, not 3.
Precision points
  • Lowest locants win — number from the end that gives the smaller set (pentan-2-ol, not pentan-4-ol).
  • Prefixes go alphabetically (ethyl before methyl), each with its own locant; di/tri do not count for alphabetising.
  • The name must match the exact structure — examiner reports flag names that are chemically related but not the compound asked for.
🧪 Exam-style questions
Q1 [1 mark]

What is the IUPAC name for this compound? Tick (✓) one box.

F
Q2 [1 mark]

Which is the IUPAC name for this compound? Tick (✓) one box.

F

Source: AQA A-Level Chemistry past papers.

Structural isomerism

Key definition

Structural isomers are compounds with the same molecular formula but a different structural formula (a different arrangement of atoms).

There are three types, and AQA expects you to classify which one you are looking at:

TypeWhat differsExample pair
Chainthe carbon skeleton (branching)butane and 2-methylpropane
Positionthe position of the functional grouppropan-1-ol and propan-2-ol
Functional groupthe functional group itselfan alkene and a cycloalkane; an aldehyde and a ketone

Chain

butane · 2-methylpropane

same formula, the skeleton branches differently

Position

OHOH

propan-1-ol · propan-2-ol

same group, different carbon

Functional group

but-1-ene · cyclobutane

an alkene and a cycloalkane — both C4H8

Same molecular formula every time — only the arrangement changes. Check the formula first, then decide which type.

Functional-group isomerism nearly always comes from one of these same-formula pairings — worth knowing cold:

Shared molecular formulaPairingExample pair
CnH2nalkene ↔ cycloalkanebut-1-ene & cyclobutane (C4H8)
CnH2n+2Oalcohol ↔ etherpropan-1-ol & methoxyethane (C3H8O)
CnH2nOaldehyde ↔ ketonepropanal & propanone (C3H6O)
CnH2nO2carboxylic acid ↔ esterpropanoic acid & methyl ethanoate (C3H6O2)
Precision points
  • Check the molecular formula first — two structures are only isomers if the formula is identical.
  • The functional-group isomer of an alkene is a cycloalkane (same CnH2n) — examiner reports flag students missing this.
  • Name the type when asked: chain, position or functional group.
🧪 Exam-style questions
Q1 [1 mark]

Which compound is an isomer of ethyl ethanoate? Tick (✓) one box.

Source: AQA A-Level Chemistry past papers.

E–Z isomerism & CIP

Key definitions

Stereoisomers have the same structural formula but a different arrangement of atoms in space.

E–Z isomerism is a form of stereoisomerism that arises from restricted rotation about the planar C=C double bond, when each carbon of the double bond carries two different groups.

That is the whole origin of E–Z isomerism: because there is no rotation about a C=C double bond, the groups are locked on their side. To label which isomer is which, use the Cahn–Ingold–Prelog (CIP) priority rules:

  • At each end of the double bond, rank the two atoms by atomic number — higher atomic number = higher priority. If the first atoms tie, look at the next atoms out.
  • If the two higher-priority groups are on the same sideZ (zusammen, together). On opposite sidesE (entgegen, opposite).
  • Cis/trans is an older naming you will still meet, used for simple alkenes — ones where each carbon of the C=C carries at least one identical substituent (usually an H on each, as in but-2-ene). Cis = the matching groups on the same side (here the same as Z); trans = opposite sides (E). Once all four groups differ, cis/trans breaks down — E–Z always works, so give E or Z in the exam.

Z-but-2-ene

C C H₃C H CH₃ H

higher priorities (CH3) togetherzusammen

E-but-2-ene

C C H₃C H H CH₃

higher priorities apartentgegen; the double bond stops rotation

CIP in action — 2-chlorobut-2-ene

C C H₃C 2 Cl 1 CH₃ 1 H 2

left C: Cl (17) beats C (6) → priority is down. right C: C beats H → is up. Opposites → this drawing is E-2-chlorobut-2-ene.

The double bond can’t rotate, so the groups are fixed either side. Rank each end by atomic number: higher priorities together is Z, apart is E.
Precision points
  • Each C of the C=C needs two different groups. A terminal or symmetrical alkene (e.g. CH2=CBr2) has no E–Z isomers.
  • Rank by atomic number, not by size or eye. Br > Cl > O > N > C > H; if tied, move to the next atom out.
  • Z = higher priorities together, E = apart — don’t assume cis/trans without checking priorities.
🧪 Exam-style questions
Q1 [1 mark]

Which alkene shows E–Z isomerism? Tick (✓) one box.

Q2 [1 mark]

Which compound has E–Z isomers? Tick (✓) one box.

Q3 [6 marks]

Explain the difference between structural isomerism and stereoisomerism. Use compounds with the molecular formula C4H8 to show stereoisomerism and the three types of structural isomerism.

Show answer

Structural isomers have the same molecular formula but a different structural formula (different arrangement of atoms). 1 mark Stereoisomers have the same structural formula but a different arrangement of atoms in space. 1 mark

Chain: but-1-ene and 2-methylpropene (methylpropene). 1 mark

Position: but-1-ene and but-2-ene. 1 mark

Functional group: butene (an alkene) and cyclobutane (a cycloalkane). 1 mark

Stereoisomerism: but-2-ene exists as E-but-2-ene and Z-but-2-ene. 1 mark

Source: AQA A-Level Chemistry past papers.

Reaction mechanisms & curly arrows

A mechanism shows how a reaction happens by tracking the movement of electrons. A-Level uses two notations, and the reactions you meet later are all written in one of them.

  • Free-radical mechanisms — an unpaired electron is shown as a dot (e.g. Cl•). You write balanced equations for each step (initiation, propagation, termination); curly arrows are not used for radicals.
  • Electron-pair mechanisms — drawn with curly arrows, each showing a pair of electrons moving.
Curly-arrow rules

A curly arrow shows a pair of electrons moving. It must start from a bond or a lone pair and point to where the new bond (or lone pair) forms. To break a bond, the arrow starts on that bond.

From a bond

Hδ+Brδ−tail on the BOND midpoint

breaking a bond: the arrow starts on that bond

From a lone pair

OHCδ+tail on the LONE PAIR

making a bond: the arrow starts on the pair that will form it

Heterolytic vs homolytic fission

ClClheterolytic · the pair → one atomClClhomolytic · one e⁻ each

full head = the pair moves · fish-hook = one electron (radicals — AQA wants equations there, not arrows)

The dodgy one

OHCδ+starts in EMPTY SPACE → no markOHCδ+starts on the electrons → mark

an arrow never starts from empty space — electrons move, and they must come from somewhere real

Get the grammar right now and every mechanism later reads cleanly: an arrow always starts on electrons — a bond or a lone pair — and its head lands exactly where they go.
Precision points
  • A curly arrow never starts from empty space. Examiner reports are explicit: it must start from a bond or a lone pair.
  • Radicals use a dot, not an arrow. Half-headed arrows and single electrons belong to radical chemistry — but the spec asks for balanced equations there, not arrows.
  • The head points where the electrons go — onto the atom or between the two atoms forming the new bond.

Capstone: read the command word

More organic marks are lost to format than to chemistry. The molecule can be perfect, but if AQA asked for a skeletal formula and you drew a displayed one, the mark is gone. Circle the command word first, then answer in exactly that form:

Command wordWhat AQA wants
Namethe full IUPAC name (locants, prefixes, stem, suffix)
Molecular formulathe actual count of each atom, e.g. C4H10O
Structural formulathe condensed arrangement, e.g. CH3CH(OH)CH3
Displayed formulaevery atom and every bond — including each O–H
Skeletal formulazig-zag with C and C–H implied; heteroatoms & their H shown
Mechanismstructures + curly arrows (from a bond or lone pair)

Same molecule, six possible answers — the exam decides which one scores. Build the habit here and it protects you on every organic question for the rest of the course.

3.3.1 Introduction to organic chemistry — Quick-reference summary
  • Six formulae: empirical (ratio), molecular (actual counts), general (algebraic pattern), structural (condensed), displayed (every atom & bond), skeletal (C and C–H implied, heteroatoms & their H shown).
  • Skeletal rules: carbon at every corner and line-end; no C–H drawn; but –OH, –NH2, –COOH are shown. Skeletal ≠ displayed — the format is marked.
  • Homologous series = same functional group, same general formula, differing by CH2, similar chemistry.
  • IUPAC naming: longest chain (stem) + principal group (suffix) + lowest locants + substituents (prefixes, alphabetical); rings get “cyclo-”. Two groups? The suffix goes to the higher priority: acid > aldehyde > ketone > alcohol > amine > alkene.
  • Structural isomers (same molecular formula, different connectivity): chain, position, functional group — common pairs: alkene ↔ cycloalkane, alcohol ↔ ether, aldehyde ↔ ketone, acid ↔ ester.
  • Stereoisomers (same structure, different spatial arrangement): E–Z from restricted rotation about a C=C, when each double-bond carbon carries two different groups. Rank by CIP (atomic number): higher priorities together = Z, apart = E.
  • Curly arrows show an electron pair moving, starting from a bond or a lone pair — never from empty space; radicals use a dot (no arrows).

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